SEQUENCE LISTING <110> SANOFI <120> ANTIBODY FORMULATIONS <130> US2016/011 US PCT; 15-2048-WO <150> US 62/358,404 <151> 2016-07-05 <150> EP 16306090.8 <151> 2016-07-30 <160> 69 <170> PatentIn version 3.5 <210> 1 <211> 36 <212> PRT <213> Homo sapiens <400> 1 Met Asn Tyr Pro Thr Leu Glu Met Asp Leu Glu Asn Leu Glu Asp Leu 1 5 10 15 Phe Trp Glu Leu Asp Arg Leu Asp Asn Tyr Asn Thr Ser Leu Val Glu 20 25 30 Asn His Leu Cys 35 <210> 2 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <220> <221> misc_feature <222> (18)..(18) <223> n is a, c, g, or t <400> 2 cttccggaat tcsargtnma gctgsagsag tc 32 <210> 3 <211> 35 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <220> <221> misc_feature <222> (18)..(18) <223> n is a, c, g, or t <400> 3 cttccggaat tcsargtnma gctgsagsag tcwgg 35 <210> 4 <211> 36 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 4 ggaggatcca tagacagatg ggggtgtcgt tttggc 36 <210> 5 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 5 ggagctcgay attgtgmtsa cmcarwctmc a 31 <210> 6 <211> 46 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 6 tatagagctc aagcttggat ggtgggaaga tggatacagt tggtgc 46 <210> 7 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 7 ccaagctgtg tcctrtcc 18 <210> 8 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 8 cgacaagtcg actagccctt gaccaggcat cc 32 <210> 9 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 9 wtctctrgag tcagtggg 18 <210> 10 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic primer <400> 10 cgactagtcg actggtggga agatggatac ag 32 <210> 11 <211> 112 <212> PRT <213> Mus sp. <400> 11 Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val Thr Pro Arg 1 5 10 15 Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Arg Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 12 <211> 111 <212> PRT <213> Mus sp. <400> 12 Gln Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Ser Gln 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Ser Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Arg Lys Asp Asn Ser Gln Ser Gln Val Phe Leu 65 70 75 80 Lys Met Asn Ser Leu Gln Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ala 100 105 110 <210> 13 <211> 112 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 13 Asp Ile Val Met Thr Gln Ser Ala Leu Ser Val Ala Val Thr Pro Gly 1 5 10 15 Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 14 <211> 112 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 14 Asp Ile Val Met Thr Gln Ser Ala Leu Ser Val Ala Val Thr Pro Gly 1 5 10 15 Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Leu Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 15 <211> 113 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 15 Asp Ile Val Met Thr Gln Ser Ala Leu Ser Val Ala Val Thr Pro Gly 1 5 10 15 Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Leu Ser Ser Asn Leu Ala Ser Gly Val 50 55 60 Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Lys 65 70 75 80 Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln 85 90 95 His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 16 <211> 111 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 16 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Ala Pro Ser Glu 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Asn Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Lys Met Asn Ser Leu Thr Ala Ala Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 100 105 110 <210> 17 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 17 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ser Ala Leu Ser Val Ala Val 20 25 30 Thr Pro Gly Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Lys Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 18 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 18 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccagagcgcc ctcagcgtgg ccgtgacccc cggcgagagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg catgagcaac 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 aagatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 19 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 19 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ser Ala Leu Ser Val Ala Val 20 25 30 Thr Pro Gly Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Leu Ser Asn Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Lys Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 20 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 20 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccagagcgcc ctcagcgtgg ccgtgacccc cggcgagagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg cctgagcaac 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 aagatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 21 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 21 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ser Ala Leu Ser Val Ala Val 20 25 30 Thr Pro Gly Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Leu Ser Ser Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Lys Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 22 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 22 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccagagcgcc ctcagcgtgg ccgtgacccc cggcgagagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg cctgagcagc 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 aagatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 23 <211> 456 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 23 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Ala 20 25 30 Pro Ser Glu Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu 35 40 45 Ile Asp Tyr Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu 50 55 60 Glu Trp Leu Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Pro 65 70 75 80 Ser Leu Lys Ser Arg Leu Ser Ile Ser Lys Asp Asn Ser Lys Ser Gln 85 90 95 Val Phe Leu Lys Met Asn Ser Leu Thr Ala Ala Asp Thr Ala Met Tyr 100 105 110 Tyr Cys Ala Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val 115 120 125 Ser Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Cys 130 135 140 Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly Cys Leu Val Lys 145 150 155 160 Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu 165 170 175 Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu 180 185 190 Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr 195 200 205 Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser Asn Thr Lys Val 210 215 220 Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys Pro Ser Cys Pro 225 230 235 240 Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 245 250 255 Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val 260 265 270 Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln Phe Asn Trp Tyr 275 280 285 Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 290 295 300 Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His 305 310 315 320 Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys 325 330 335 Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln 340 345 350 Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Ser Gln Glu Glu Met 355 360 365 Thr Lys Asn Gln Val Ser Leu Thr Cys Leu Val Lys Gly Phe Tyr Pro 370 375 380 Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn 385 390 395 400 Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 405 410 415 Tyr Ser Arg Leu Thr Val Asp Lys Ser Arg Trp Gln Glu Gly Asn Val 420 425 430 Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr Thr Gln 435 440 445 Lys Ser Leu Ser Leu Ser Leu Gly 450 455 <210> 24 <211> 1385 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 24 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagccagg tgcagctgca ggagagcggc cccggcctgg tggcccccag cgagagcctg 120 agcatcacct gcaccgtgag cggcttcagc ctgatcgact acggcgtgaa ctggatccgc 180 cagccccccg gcaagggcct ggagtggctg ggcgtgatct ggggcgacgg caccacctac 240 tacaacccca gcctgaagag ccgcctgagc atctccaagg acaacagcaa gagccaggtg 300 ttcctgaaga tgaacagcct gaccgccgcc gacaccgcca tgtactactg cgcccgcatc 360 gtgtactggg gccagggcac cctggtgacc gtgagcagcg ccagcaccaa gggcccttcc 420 gtgttccctc tggccccttg ctcccggtcc acctccgagt ccaccgccgc tctgggctgc 480 ctggtgaagg actacttccc tgagcctgtg accgtgtcct ggaactctgg cgccctgacc 540 tccggcgtgc acaccttccc tgccgtgctg cagtcctccg gcctgtactc cctgtcctcc 600 gtggtgaccg tgccttcctc ctccctgggc accaagacct acacctgtaa cgtggaccac 660 aagccttcca acaccaaggt ggacaagcgg gtggagtcca agtacggccc tccttgccct 720 tcctgccctg cccctgagtt cctgggcgga cctagcgtgt tcctgttccc tcctaagcct 780 aaggacaccc tgatgatctc ccggacccct gaggtgacct gtgtggtggt ggacgtgtcc 840 caggaggacc ctgaggtcca gttcaactgg tacgtggacg gcgtggaggt gcacaacgcc 900 aagaccaagc ctcgggagga gcagttcaat tccacctacc gggtggtgtc tgtgctgacc 960 gtgctgcacc aggactggct gaacggcaaa gaatacaagt gtaaggtctc caacaagggc 1020 ctgccctcct ccatcgagaa aaccatctcc aaggccaagg gccagcctag ggagcctcag 1080 gtgtacaccc tgcctcctag ccaggaagag atgaccaaga accaggtgtc cctgacctgt 1140 ctggtgaagg gcttctaccc ttccgacatc gccgtggagt gggagtccaa cggccagcct 1200 gagaacaact acaagaccac ccctcctgtg ctggactccg acggctcctt cttcctgtac 1260 tccaggctga ccgtggacaa gtcccggtgg caggagggca acgtcttttc ctgctccgtg 1320 atgcacgagg ccctgcacaa ccactacacc cagaagtccc tgtccctgtc tctgggctga 1380 agctt 1385 <210> 25 <211> 22 <212> PRT <213> Homo sapiens <400> 25 Lys Pro Gly Gln Pro Pro Arg Leu Leu Ile Tyr Asp Ala Ser Asn Arg 1 5 10 15 Ala Thr Gly Ile Pro Ala 20 <210> 26 <211> 12 <212> PRT <213> Mus musculus <400> 26 Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ile 1 5 10 <210> 27 <211> 12 <212> PRT <213> Homo sapiens <400> 27 Ser Glu Asp Ser Ala Leu Tyr Tyr Cys Ala Arg Asp 1 5 10 <210> 28 <211> 112 <212> PRT <213> Mus musculus <400> 28 Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val Thr Pro Arg 1 5 10 15 Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Arg Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 29 <211> 111 <212> PRT <213> Mus musculus <400> 29 Gln Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Ser Gln 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Ser Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Arg Lys Asp Asn Ser Gln Ser Gln Val Phe Leu 65 70 75 80 Lys Met Asn Ser Leu Gln Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ala 100 105 110 <210> 30 <211> 112 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 30 Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val Thr Pro Gly 1 5 10 15 Ala Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Arg Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 31 <211> 112 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 31 Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val Thr Pro Gly 1 5 10 15 Ala Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Leu Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Arg Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 32 <211> 112 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 32 Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val Thr Pro Gly 1 5 10 15 Ala Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Leu Ser Ser Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Arg Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 33 <211> 111 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 33 Gln Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Ser Glu 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Asn Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Lys Val Thr Ser Leu Thr Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ala 100 105 110 <210> 34 <211> 111 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 34 Glu Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Gly Gly 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Ala Pro Leu Lys 50 55 60 Gly Arg Leu Ser Ile Ser Lys Asp Asn Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Gln Met Asn Ser Leu Lys Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 100 105 110 <210> 35 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 35 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val 20 25 30 Thr Pro Arg Glu Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Arg Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 36 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 36 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccaggccgcc cccagcgtgg ccgtgacccc ccgcgagagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg catgagcaac 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 cgcatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 37 <211> 456 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 37 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Gln Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala 20 25 30 Pro Ser Gln Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu 35 40 45 Ile Asp Tyr Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu 50 55 60 Glu Trp Leu Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Ser 65 70 75 80 Ala Leu Lys Ser Arg Leu Ser Ile Arg Lys Asp Asn Ser Gln Ser Gln 85 90 95 Val Phe Leu Lys Met Asn Ser Leu Gln Thr Asp Asp Thr Ala Met Tyr 100 105 110 Tyr Cys Ala Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val 115 120 125 Ser Ala Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Cys 130 135 140 Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly Cys Leu Val Lys 145 150 155 160 Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu 165 170 175 Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu 180 185 190 Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr 195 200 205 Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser Asn Thr Lys Val 210 215 220 Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys Pro Ser Cys Pro 225 230 235 240 Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 245 250 255 Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val 260 265 270 Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln Phe Asn Trp Tyr 275 280 285 Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 290 295 300 Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His 305 310 315 320 Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys 325 330 335 Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln 340 345 350 Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Ser Gln Glu Glu Met 355 360 365 Thr Lys Asn Gln Val Ser Leu Thr Cys Leu Val Lys Gly Phe Tyr Pro 370 375 380 Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn 385 390 395 400 Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 405 410 415 Tyr Ser Arg Leu Thr Val Asp Lys Ser Arg Trp Gln Glu Gly Asn Val 420 425 430 Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr Thr Gln 435 440 445 Lys Ser Leu Ser Leu Ser Leu Gly 450 455 <210> 38 <211> 1385 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 38 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagccagg tgcagctgaa ggagagcggc cccggcctgg tggcccccag ccagagcctg 120 agcatcacct gcaccgtgag cggcttcagc ctgatcgact acggcgtgaa ctggatccgc 180 cagccccccg gcaagggcct ggagtggctg ggcgtgatct ggggcgacgg caccacctac 240 tacaacagcg ccctgaagag ccgcctgagc atccgcaagg acaacagcca gagccaggtg 300 ttcctgaaga tgaacagcct gcagaccgac gacaccgcca tgtactactg cgcccgcatc 360 gtgtactggg gccagggcac cctggtgacc gtgagcgccg ccagcaccaa gggcccttcc 420 gtgttccctc tggccccttg ctcccggtcc acctccgagt ccaccgccgc tctgggctgc 480 ctggtgaagg actacttccc tgagcctgtg accgtgtcct ggaactctgg cgccctgacc 540 tccggcgtgc acaccttccc tgccgtgctg cagtcctccg gcctgtactc cctgtcctcc 600 gtggtgaccg tgccttcctc ctccctgggc accaagacct acacctgtaa cgtggaccac 660 aagccttcca acaccaaggt ggacaagcgg gtggagtcca agtacggccc tccttgccct 720 tcctgccctg cccctgagtt cctgggcgga cctagcgtgt tcctgttccc tcctaagcct 780 aaggacaccc tgatgatctc ccggacccct gaggtgacct gtgtggtggt ggacgtgtcc 840 caggaggacc ctgaggtcca gttcaactgg tacgtggacg gcgtggaggt gcacaacgcc 900 aagaccaagc ctcgggagga gcagttcaat tccacctacc gggtggtgtc tgtgctgacc 960 gtgctgcacc aggactggct gaacggcaaa gaatacaagt gtaaggtctc caacaagggc 1020 ctgccctcct ccatcgagaa aaccatctcc aaggccaagg gccagcctag ggagcctcag 1080 gtgtacaccc tgcctcctag ccaggaagag atgaccaaga accaggtgtc cctgacctgt 1140 ctggtgaagg gcttctaccc ttccgacatc gccgtggagt gggagtccaa cggccagcct 1200 gagaacaact acaagaccac ccctcctgtg ctggactccg acggctcctt cttcctgtac 1260 tccaggctga ccgtggacaa gtcccggtgg caggagggca acgtcttttc ctgctccgtg 1320 atgcacgagg ccctgcacaa ccactacacc cagaagtccc tgtccctgtc tctgggctga 1380 agctt 1385 <210> 39 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 39 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val 20 25 30 Thr Pro Gly Ala Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Arg Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 40 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 40 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccaggccgcc cccagcgtgg ccgtgacccc cggcgccagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg catgagcaac 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 cgcatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 41 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 41 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val 20 25 30 Thr Pro Gly Ala Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Leu Ser Asn Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Arg Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 42 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 42 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccaggccgcc cccagcgtgg ccgtgacccc cggcgccagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg cctgagcaac 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 cgcatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 43 <211> 238 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 43 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val 20 25 30 Thr Pro Gly Ala Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu 35 40 45 Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Arg Pro 50 55 60 Gly Gln Ser Pro Gln Leu Leu Ile Tyr Arg Leu Ser Ser Leu Ala Ser 65 70 75 80 Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr 85 90 95 Leu Arg Ile Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys 100 105 110 Met Gln His Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu 115 120 125 Glu Ile Lys Arg Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro 130 135 140 Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu 145 150 155 160 Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn 165 170 175 Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser 180 185 190 Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala 195 200 205 Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly 210 215 220 Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 225 230 235 <210> 44 <211> 731 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 44 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgaca tcgtgatgac ccaggccgcc cccagcgtgg ccgtgacccc cggcgccagc 120 gtgagcatca gctgccgcag cagcaagagc ctgctgcaca gcagcggcaa gacctacctg 180 tactggttcc tgcagcgccc cggccagagc ccccagctgc tgatctaccg cctgagcagc 240 ctggccagcg gcgtgcccga ccgcttcagc ggcagcggca gcggcaccgc cttcaccctg 300 cgcatcagcc gcgtggaggc cgaggacgtg ggcgtgtact actgcatgca gcacctggag 360 tacccctaca ccttcggcgg cggcaccaag ctggagatca agcgtacggt ggccgctcct 420 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 480 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 540 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 600 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 660 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 720 tgctgaagct t 731 <210> 45 <211> 456 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 45 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Gln Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala 20 25 30 Pro Ser Glu Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu 35 40 45 Ile Asp Tyr Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu 50 55 60 Glu Trp Leu Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Pro 65 70 75 80 Ser Leu Lys Ser Arg Leu Ser Ile Ser Lys Asp Asn Ser Lys Ser Gln 85 90 95 Val Phe Leu Lys Val Thr Ser Leu Thr Thr Asp Asp Thr Ala Met Tyr 100 105 110 Tyr Cys Ala Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val 115 120 125 Ser Ala Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Cys 130 135 140 Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly Cys Leu Val Lys 145 150 155 160 Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu 165 170 175 Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu 180 185 190 Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr 195 200 205 Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser Asn Thr Lys Val 210 215 220 Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys Pro Ser Cys Pro 225 230 235 240 Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 245 250 255 Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val 260 265 270 Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln Phe Asn Trp Tyr 275 280 285 Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 290 295 300 Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His 305 310 315 320 Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys 325 330 335 Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln 340 345 350 Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Ser Gln Glu Glu Met 355 360 365 Thr Lys Asn Gln Val Ser Leu Thr Cys Leu Val Lys Gly Phe Tyr Pro 370 375 380 Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn 385 390 395 400 Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 405 410 415 Tyr Ser Arg Leu Thr Val Asp Lys Ser Arg Trp Gln Glu Gly Asn Val 420 425 430 Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr Thr Gln 435 440 445 Lys Ser Leu Ser Leu Ser Leu Gly 450 455 <210> 46 <211> 1385 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 46 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagccagg tgcagctgaa ggagagcggc cccggcctgg tggcccccag cgagagcctg 120 agcatcacct gcaccgtgag cggcttcagc ctgatcgact acggcgtgaa ctggatccgc 180 cagccccccg gcaagggcct ggagtggctg ggcgtgatct ggggcgacgg caccacctac 240 tacaacccca gcctgaagag ccgcctgagc atcagcaagg acaacagcaa gagccaggtg 300 ttcctgaagg tgaccagcct gaccaccgac gacaccgcca tgtactactg cgcccgcatc 360 gtgtactggg gccagggcac cctggtgacc gtgagcgccg ccagcaccaa gggcccttcc 420 gtgttccctc tggccccttg ctcccggtcc acctccgagt ccaccgccgc tctgggctgc 480 ctggtgaagg actacttccc tgagcctgtg accgtgtcct ggaactctgg cgccctgacc 540 tccggcgtgc acaccttccc tgccgtgctg cagtcctccg gcctgtactc cctgtcctcc 600 gtggtgaccg tgccttcctc ctccctgggc accaagacct acacctgtaa cgtggaccac 660 aagccttcca acaccaaggt ggacaagcgg gtggagtcca agtacggccc tccttgccct 720 tcctgccctg cccctgagtt cctgggcgga cctagcgtgt tcctgttccc tcctaagcct 780 aaggacaccc tgatgatctc ccggacccct gaggtgacct gtgtggtggt ggacgtgtcc 840 caggaggacc ctgaggtcca gttcaactgg tacgtggacg gcgtggaggt gcacaacgcc 900 aagaccaagc ctcgggagga gcagttcaat tccacctacc gggtggtgtc tgtgctgacc 960 gtgctgcacc aggactggct gaacggcaaa gaatacaagt gtaaggtctc caacaagggc 1020 ctgccctcct ccatcgagaa aaccatctcc aaggccaagg gccagcctag ggagcctcag 1080 gtgtacaccc tgcctcctag ccaggaagag atgaccaaga accaggtgtc cctgacctgt 1140 ctggtgaagg gcttctaccc ttccgacatc gccgtggagt gggagtccaa cggccagcct 1200 gagaacaact acaagaccac ccctcctgtg ctggactccg acggctcctt cttcctgtac 1260 tccaggctga ccgtggacaa gtcccggtgg caggagggca acgtcttttc ctgctccgtg 1320 atgcacgagg ccctgcacaa ccactacacc cagaagtccc tgtccctgtc tctgggctga 1380 agctt 1385 <210> 47 <211> 456 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 47 Met Gly Trp Ser Cys Ile Ile Leu Phe Leu Val Ala Thr Ala Thr Gly 1 5 10 15 Val His Ser Glu Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala 20 25 30 Pro Gly Gly Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu 35 40 45 Ile Asp Tyr Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu 50 55 60 Glu Trp Leu Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Ala 65 70 75 80 Pro Leu Lys Gly Arg Leu Ser Ile Ser Lys Asp Asn Ser Lys Ser Gln 85 90 95 Val Phe Leu Gln Met Asn Ser Leu Lys Thr Asp Asp Thr Ala Met Tyr 100 105 110 Tyr Cys Ala Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val 115 120 125 Ser Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Cys 130 135 140 Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly Cys Leu Val Lys 145 150 155 160 Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu 165 170 175 Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu 180 185 190 Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr 195 200 205 Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser Asn Thr Lys Val 210 215 220 Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys Pro Ser Cys Pro 225 230 235 240 Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 245 250 255 Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val 260 265 270 Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln Phe Asn Trp Tyr 275 280 285 Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 290 295 300 Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His 305 310 315 320 Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys 325 330 335 Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln 340 345 350 Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Ser Gln Glu Glu Met 355 360 365 Thr Lys Asn Gln Val Ser Leu Thr Cys Leu Val Lys Gly Phe Tyr Pro 370 375 380 Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn 385 390 395 400 Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 405 410 415 Tyr Ser Arg Leu Thr Val Asp Lys Ser Arg Trp Gln Glu Gly Asn Val 420 425 430 Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr Thr Gln 435 440 445 Lys Ser Leu Ser Leu Ser Leu Gly 450 455 <210> 48 <211> 1385 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polynucleotide <400> 48 gctagcacca tgggctggag ctgcatcatc ctgttcctgg tggccaccgc caccggcgtg 60 cacagcgagg tgcagctgaa ggagagcggc cccggcctgg tggcccccgg cggcagcctg 120 agcatcacct gcaccgtgag cggcttcagc ctgatcgact acggcgtgaa ctggatccgc 180 cagccccccg gcaagggcct ggagtggctg ggcgtgatct ggggcgacgg caccacctac 240 tacaacgccc ccctgaaggg ccgcctgagc atcagcaagg acaacagcaa gagccaggtg 300 ttcctgcaga tgaacagcct gaagaccgac gacaccgcca tgtactactg cgcccgcatc 360 gtgtactggg gccagggcac cctggtgacc gtgagcagcg ccagcaccaa gggcccttcc 420 gtgttccctc tggccccttg ctcccggtcc acctccgagt ccaccgccgc tctgggctgc 480 ctggtgaagg actacttccc tgagcctgtg accgtgtcct ggaactctgg cgccctgacc 540 tccggcgtgc acaccttccc tgccgtgctg cagtcctccg gcctgtactc cctgtcctcc 600 gtggtgaccg tgccttcctc ctccctgggc accaagacct acacctgtaa cgtggaccac 660 aagccttcca acaccaaggt ggacaagcgg gtggagtcca agtacggccc tccttgccct 720 tcctgccctg cccctgagtt cctgggcgga cctagcgtgt tcctgttccc tcctaagcct 780 aaggacaccc tgatgatctc ccggacccct gaggtgacct gtgtggtggt ggacgtgtcc 840 caggaggacc ctgaggtcca gttcaactgg tacgtggacg gcgtggaggt gcacaacgcc 900 aagaccaagc ctcgggagga gcagttcaat tccacctacc gggtggtgtc tgtgctgacc 960 gtgctgcacc aggactggct gaacggcaaa gaatacaagt gtaaggtctc caacaagggc 1020 ctgccctcct ccatcgagaa aaccatctcc aaggccaagg gccagcctag ggagcctcag 1080 gtgtacaccc tgcctcctag ccaggaagag atgaccaaga accaggtgtc cctgacctgt 1140 ctggtgaagg gcttctaccc ttccgacatc gccgtggagt gggagtccaa cggccagcct 1200 gagaacaact acaagaccac ccctcctgtg ctggactccg acggctcctt cttcctgtac 1260 tccaggctga ccgtggacaa gtcccggtgg caggagggca acgtcttttc ctgctccgtg 1320 atgcacgagg ccctgcacaa ccactacacc cagaagtccc tgtccctgtc tctgggctga 1380 agctt 1385 <210> 49 <211> 5 <212> PRT <213> Homo sapiens <400> 49 Glu Leu Leu Gly Gly 1 5 <210> 50 <211> 5 <212> PRT <213> Homo sapiens <400> 50 Met Ile Ser Arg Thr 1 5 <210> 51 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic 6x His tag <400> 51 His His His His His His 1 5 <210> 52 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 52 Pro Gly Lys Ala Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu 1 5 10 15 <210> 53 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 53 Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu 1 5 10 15 <210> 54 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 54 Ser Leu Ile Asp Tyr Gly Val Asn Trp Ile Arg Gln Pro Pro Gly 1 5 10 15 <210> 55 <211> 112 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 55 Asp Ile Val Met Thr Gln Ala Ala Pro Ser Val Ala Val Thr Pro Gly 1 5 10 15 Gln Ser Val Ser Ile Ser Cys Arg Ser Ser Lys Ser Leu Leu His Ser 20 25 30 Ser Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln His Pro Gly Lys Ala 35 40 45 Pro Gln Leu Leu Ile Tyr Arg Met Ser Asn Leu Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Ala Phe Thr Leu Thr Ile 65 70 75 80 Ser Gly Val Gln Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln His 85 90 95 Leu Glu Tyr Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 56 <211> 113 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 56 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Ala Pro Ser Gln 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Asn Ser Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Thr Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Lys Met Asn Ser Leu Thr Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ala Ala 100 105 110 Lys <210> 57 <211> 113 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic polypeptide <400> 57 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Ala Pro Ser Gln 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Asp Tyr 20 25 30 Gly Val Asn Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Gly Asp Gly Thr Thr Tyr Tyr Pro Ser Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Thr Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Lys Met Asn Ser Leu Thr Thr Asp Asp Thr Ala Met Tyr Tyr Cys Ala 85 90 95 Arg Ile Val Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ala Ala 100 105 110 Lys <210> 58 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 58 Arg Ser Ser Lys Ser Leu Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr 1 5 10 15 <210> 59 <211> 7 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 59 Arg Met Ser Asn Leu Ala Ser 1 5 <210> 60 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 60 Met Gln His Leu Glu Tyr Pro Tyr Thr 1 5 <210> 61 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 61 Gly Phe Ser Leu Ile Asp Tyr Gly Val Asn 1 5 10 <210> 62 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 62 Val Ile Trp Gly Asp Gly Thr Thr Tyr 1 5 <210> 63 <211> 3 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 63 Ile Val Tyr 1 <210> 64 <211> 7 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 64 Arg Leu Ser Asn Leu Ala Ser 1 5 <210> 65 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 65 Arg Leu Ser Ser Asn Leu Ala Ser 1 5 <210> 66 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 66 Arg Met Ser Asn Leu Ala 1 5 <210> 67 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 67 Arg Leu Ser Asn Leu Ala 1 5 <210> 68 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 68 Arg Leu Ser Ser Leu Ala 1 5 <210> 69 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 69 Arg Ser Ser Lys Ser Leu Leu His Ser Ser Gly Lys Thr Tyr Leu Tyr 1 5 10 15 Trp